Abstract

A novel mouse gene full-length cDNA sequence—SRG2 were identified (GenBank accession number AF395083), which was significantly changed in cryptorchidism, from a mouse testis cDNA library using a cDNA fragment (GenBank accession number BE644542) as an electronic probe. SRG2 was 1058 bp in length. The putative protein encoded by this gene was 295 amino acids with a theoretical molecular weight of 33 579 and isoelectric point of 9.64. The sequence shared no signi fican t homology with any known protein in databases except TSARG2, with which its hom ology was 78%. RT-PCR showed that SRG2 was expressed significantly in testis.